AMD 

100-506116 AMD INSTINCT MI100

Mfg Part Number:  100-506116  
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Last Updated: Oct 12, 2025
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Introducing AMD Instinct™ MI100 Accelerator

First Data Center GPU to Surpass 10TF FP64 Barrier

Accelerate Your Discoveries

AMD Instinct™ MI100 accelerator is the world's fastest HPC GPU, engineered from the ground up for the new era of computing. Powered by the AMD CDNA architecture, the MI100 accelerators deliver a giant leap in compute and interconnect performance, offering a nearly 3.5x the boost for HPC (FP32 matrix) and a nearly 7x boost for AI (FP16) throughput compared to prior generation AMD accelerators.

MI100 accelerators supported by AMDROCm™, the industry's first open software platform, offer customers an open platform that helps eliminate vendor lock-in, enabling developers to enhance existing GPU codes to run everywhere. Combined with the award winning AMD EPYC™ processors and AMD Infinity Fabric™ technology, MI100-powered systems provide scientists and researchers platforms that propel discoveries today and prepare them for exascale tomorrow.

Designed on AMD CDNA Architecture with 120 Compute Units (7,680 cores)

World's Fastest HPC GPU with up to 11.5 TFLOPs Peak FP64 Performance

Up to 46.1 TFLOPs FP32 Matrix Peak Performance with All-New Matrix Cores for HPC & AI Workloads

Up to 184.6 TFLOPs FP16 & 92.3 TFLOPs bFloat16 Peak for Ultra-Fast AI Training

32 GB Ultra-fast HBM2 ECC Memory with upto 1.2 TB/s Memory Bandwidth

Open & Portable AMD ROCm™ Ecosystem

2nd Gen Infinity Architecture with up to 340 GB/s of aggregate P2P GPU I/O bandwidth

PCIe® Gen 4 x16 Ready GPU

World's Fastest HPC GPU

Delivering up to 11.5 TFLOPs of double precision (FP64) theoretical peak performance, the AMD Instinct™ MI100 accelerator delivers leadership performance for HPC applications and a substantial up-lift in performance over previous gen AMD accelerators. The MI100 delivers up to a 74% generational double precision performance boost for HPC applications.

Main Specification
General Information
Manufacturer Advanced Micro Devices, Inc
Manufacturer Part Number 100-506116
Manufacturer Website Address http://www.amd.com
Brand Name AMD
Product Name Instinct MI100 Accelerator
Product Type Graphic Card
Technical Information
API Supported OpenGL 4.6
API Supported OpenCL
API Supported Vulkan 1.0
API Supported OpenCL 2.0
Processor & Chipset
Chipset Manufacturer AMD
Chipset Line Instinct
Chipset Series MI
Chipset Model MI100
GPU Boost Clock 1.50 GHz
Memory
Standard Memory 32 GB
Memory Technology HBM2
Bus Width 4096 bit
Interfaces/Ports
Host Interface PCI Express 4.0 x16
Physical Characteristics
Slot Space Required Dual
Form Factor Plug-in Card
Card Height Full-height
Cooler Type Passive Cooler
Length 12"
Miscellaneous
Platform Supported Linux
Platform Supported PC
WARNING:: The plastic used in cable products can expose you to lead and lead components, chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information go to www.P65Warnings.ca.gov
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